漫画 | 视觉细胞(II)中间层家族

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原文链接: zhuanlan.zhihu.com

​上一期,我们介绍了住在视网膜村子最里面的感光家族——

视椎和视杆(戳这里回顾)

他们将光信号转换成了电信号

然后将外界信息传递给视网膜中间层家族做进一步加工:

策划:

脚本:

绘画:@鹄羽


有两个地方更正一下:

1. 中间神经元interneuron一般特指抑制性神经元;
2. 光感受器细胞在黑暗环境下持续释放谷氨酸,有光照时cAMP水解Na+通道关闭,细胞复极化,谷氨酸释放减少。本文将其简化为有光时释放电信号,但神经递质层面上是相反的过程

—— 多谢同行居大佬指正o(`ω´ )o

作者有话说:

视觉神经科学作为较成熟的研究领域,已有很多经典的理论模型和框架,并对其他领域(如计算机视觉,人工神经网络)有所启发。但随着科技进步,现今仍不断有新的发现对领域内经典理论提出挑战,也有更多问题尚未解决。本期所列出的几种细胞,他们的功能仍未完全清楚,但是这种不确定性和多样性不正是生命的迷人之处吗?

我们漫画的出发点是希望大家初步了解这个领域,产生兴趣,发现“哦,原来“看”世界不是一件容易的事情呀~”。欢迎大家提出问题与建议,随时与我们交流~



排版:小箱子

Reference
1. Arshavsky, V. Y., & Burns, M. E. (2012). Photoreceptor signaling: supporting vision across a wide range of light intensities. Journal of Biological Chemistry, 287(3), 1620-1626.
2. Bloom, F. E., Spitzer, N. C., Gage, F., & Albright, T. (2009). Encyclopedia of Neuroscience (Vol. 1). Academic Press.
3. Borges, S. A. L. V. A. D. O. R., & Wilson, M. A. R. T. I. N. (1987). Structure of the receptive fields of bipolar cells in the salamander retina. Journal of neurophysiology, 58(6), 1275-1291.
4. Chapot, C. A., Euler, T., & Schubert, T. (2017). How do horizontal cells ‘talk’to cone photoreceptors? Different levels of complexity at the cone–horizontal cell synapse. The Journal of physiology, 595(16), 5495-5506.
5. Dulbecco, R. (1991). Encyclopedia of human biology.Academic Press.
6. Enroth-Cugell, C., & Robson, J. G. (1966). The contrast sensitivity of retinal ganglion cells of the cat. The Journal of physiology, 187(3), 517-552.
7. Feher, J. J. (2012). Quantitative human physiology.Academic press.
8. Kay, J. N., Chu, M. W., & Sanes, J. R. (2012). MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature, 483(7390), 465-469.
9. Tinsley, J. N., Molodtsov, M. I., Prevedel, R., Wartmann, D., Espigulé-Pons, J., Lauwers, M., & Vaziri, A. (2016). Direct detection of a single photon by humans. Nature communications, 7, 12172.
10. Zhang, A. J., & Wu, S. M. (2009). Receptive fields of retinal bipolar cells are mediated by heterogeneous synaptic circuitry. Journal of Neuroscience, 29(3), 789-797
https://hypertextbook.com/facts/2001/YanaNisanov1.shtml
https://thebrain.mcgill.ca/flash/d/d_02/d_02_cl/d_02_cl_vis/d_02_cl_vis.html
https://medium.com/cortically-magnified/estimating-the-number-of-photons-that-hit-the-eye-c0208e7e0b64
https://www.sciencedirect.com/topics/engineering/bipolar-cell


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